Traditional Chinese medicine: herb-drug interactions with aspirin

Singapore Med J. 2018 May;59(5):230-239. doi: 10.11622/smedj.2018051.

Abstract

Traditional Chinese medicine (TCM)-based herbal therapies have gained increasing popularity worldwide, raising concerns of its efficacy, safety profile and potential interactions with Western medications. Antithrombotic agents are among the most common prescription drugs involved in herb-drug interactions, and this article focused on aspirin, one of the most widely used antiplatelet agents worldwide. We discussed herbs that have potential interactions by exploring Western and TCM approaches to thrombotic events. Common TCM indications for these herbs were also highlighted, including possible scenarios of their concurrent usage with aspirin. With greater awareness and understanding of potential herb-drug interactions, TCM and Western physicians may collaborate more closely to identify, treat and, most importantly, prevent adverse drug events.

Keywords: antiplatelet; aspirin; herb-drug interactions; traditional Chinese medicine.

Publication types

  • Review

MeSH terms

  • Aspirin / therapeutic use*
  • Carthamus
  • Drug-Related Side Effects and Adverse Reactions
  • Drugs, Chinese Herbal / therapeutic use*
  • Herb-Drug Interactions*
  • Humans
  • Medicine, Chinese Traditional
  • Panax
  • Physicians
  • Platelet Aggregation Inhibitors / therapeutic use
  • Salvia
  • Thrombosis / drug therapy

Substances

  • Drugs, Chinese Herbal
  • Platelet Aggregation Inhibitors
  • Aspirin