Novel Stereoscopic Optical System for Objectively Measuring Above-Surface Scar Volume-First-Time Quantification of Responses to Various Treatment Modalities

Dermatol Surg. 2018 Jun;44(6):848-854. doi: 10.1097/DSS.0000000000001434.


Background: Current approaches use subjective semiquantitative or cumbersome objective methodologies to assess physical characteristics of hypertrophic and keloid scars.

Objective: This pilot study aimed to evaluate the accuracy and feasibility of a new stereoscopic optical and high-resolution 3-dimensional imaging system, for objectively measuring changes in above-surface scar volume after various interventions.

Methods: Feasibility and accuracy were assessed by monitoring the above-surface scar volume of 5 scars in 2 patients for 5 successive months. Above-surface scar volume and Vancouver Scar Scale scores and the investigator and patient volume improvement assessment scores were assessed before and 12 weeks after last intervention.

Results: Scar volume measured by the imaging system correlated significantly with the gold standard (actual weight). The greatest volume reduction followed a combination of cryotherapy and intralesional triamcinolone acetonide and 5-fluorouracil injections in Patient 1 and a combination of pulse dye laser and intralesional triamcinolone acetonide injections in Patient 2.

Conclusion: The new stereoscopic optical system is a valid, accurate, and practical objective method for assessing scar volume and for monitoring treatment response. It is more sensitive and accurate than semiquantitative objective scales. Further studies with a higher number of patients and scars are required to increase the measurement validity of the system.

MeSH terms

  • Adult
  • Cicatrix, Hypertrophic / diagnostic imaging*
  • Cicatrix, Hypertrophic / therapy
  • Cryosurgery / methods
  • Dermatologic Agents / administration & dosage
  • Feasibility Studies
  • Female
  • Fluorouracil / administration & dosage
  • Humans
  • Imaging, Three-Dimensional* / methods
  • Injections, Intralesional
  • Keloid / diagnostic imaging*
  • Keloid / therapy
  • Optical Devices*
  • Photogrammetry
  • Pilot Projects
  • Treatment Outcome
  • Triamcinolone Acetonide / administration & dosage


  • Dermatologic Agents
  • Triamcinolone Acetonide
  • Fluorouracil