Acute vertebral-basilar thrombosis. Angiologic-clinical comparison and therapeutic implications

Acta Radiol Suppl. 1986;369:38-42.


The clinical-angiologic data and the clinical outcome in 66 patients with acute vertebro-basilar thrombosis treated with antiplatelet agents, anticoagulants, or fibrinolytic agents are presented. Forty-three patients were treated with local intraarterial infusion of streptokinase or urokinase proximal to the thrombotic occlusion; 14 patients in this group (33%) survived, only one of whom was in deep coma when therapy was started. Twenty-three patients did not receive fibrinolytic therapy; 4 of these patients (17%) who exhibited mild brainstem-related symptoms survived. This study implies that early diagnosis and treatment in vertebrobasilar stroke in progression may achieve improved survival.

Publication types

  • Comparative Study

MeSH terms

  • Acute Disease
  • Adult
  • Aged
  • Angiography
  • Basilar Artery / diagnostic imaging
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Retrospective Studies
  • Thrombosis / complications
  • Thrombosis / diagnosis*
  • Thrombosis / diagnostic imaging
  • Thrombosis / drug therapy
  • Vertebral Artery / diagnostic imaging
  • Vertebrobasilar Insufficiency / diagnosis*
  • Vertebrobasilar Insufficiency / diagnostic imaging
  • Vertebrobasilar Insufficiency / drug therapy
  • Vertebrobasilar Insufficiency / etiology