Myoepithelioma of the head and neck: case report and review

J Surg Oncol. 1985 Jan;28(1):21-8. doi: 10.1002/jso.2930280107.


The clinical, light, and ultrastructure features of a myoepithelioma occurring on the hard palate of a 24-year-old woman are presented and compared with 41 myoepithelioma of the head and neck described in the English literature. These 42 tumors (39 benign and 3 malignant) occurred in individuals from 14 to 81 years of age, affected both sexes about equally, and most often presented as a slowly enlarging, asymptomatic mass. The parotid gland and palate were the most common sites of occurrence. The tumors are typically circumscribed and encapsulated, vary from 1 to 5 cm in the greatest dimension, and are composed of spindled and/or plasmacytoid myoepithelial cells. Prognosis correlates with histologic appearance and parallels that of the pleomorphic adenoma. Conservative excision with a margin of uninvolved tissue is curative. The differential diagnosis and histogenic relationship with other closely related neoplasms are discussed.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Adenoma, Pleomorphic / pathology
  • Adolescent
  • Adult
  • Aged
  • Female
  • Head and Neck Neoplasms / pathology*
  • Humans
  • Male
  • Microscopy, Electron
  • Middle Aged
  • Myoepithelioma / pathology*
  • Myoepithelioma / ultrastructure
  • Palatal Neoplasms / pathology*
  • Palatal Neoplasms / ultrastructure
  • Plasma Cells / pathology