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. 2018 Jul;40(7):e1700225.
doi: 10.1002/bies.201700225. Epub 2018 May 30.

Concise Language Promotes Clear Thinking About Cell Shape and Locomotion

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Concise Language Promotes Clear Thinking About Cell Shape and Locomotion

Lillian K Fritz-Laylin et al. Bioessays. .
Free PMC article

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Three examples of a single morphological terms used for similar-looking protrusions built by distinct molecular mechanisms.
“Lamellipod” can refer to branch-actin filled protrusions build by fibroblasts as well as thin sheets build by polymers of the unrelated Major Sperm Protein. “Lobose pseudopods” can result from either actin polymer assembly or membrane delaminations (“blebs”). “Filose pseudopods” can be built by either linear actin bundles or by microtubules. We chose these particularly obvious examples to highlight the issue; many organisms have had these and other terms applied without any knowledge of underlying molecular mechanisms.

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