Daily tadalafil for the chronic phase of stuttering priapism: a case report

BMC Urol. 2018 May 31;18(1):54. doi: 10.1186/s12894-018-0368-x.

Abstract

Background: Recurrent (stuttering) ischemic priapism is a challenging clinical condition. Frequent recurrences result in frequent hospital admissions whereas treatment with a shunting procedure often results in erectile dysfunction.

Case presentation: A 22-year-old man with stuttering idiopathic priapism developed erectile dysfunction (IIEF-5 score 12) following a Winter's shunt; he was given tadalafil, 5 mg/daily, for 6 months. This treatment resulted in progressive restoration of erectile function in the 6 months following the shunt as well as in preventing recurrence of priapic episodes over a 24-month follow-up.

Conclusions: This is the first report in literature of chronic treatment of stuttering priapism with a phosphodiesterase-5 inhibitor being able not only to prevent recurrent priapic episodes but also to restore erectile function following a Winter's shunt.

Keywords: Erectile dysfunction; PDE-5 i; Priapism; Tadalafil; Winter’s shunt.

Publication types

  • Case Reports

MeSH terms

  • Drug Administration Schedule
  • Follow-Up Studies
  • Humans
  • Male
  • Priapism / diagnosis*
  • Priapism / drug therapy*
  • Tadalafil / administration & dosage*
  • Vasodilator Agents / administration & dosage*
  • Young Adult

Substances

  • Vasodilator Agents
  • Tadalafil