Introduction: Diabetes is prevalent in India. This study was conducted to assess the impact of ingestion of fenugreek seed on fasting blood glucose levels and glycosylated hemoglobin (HbA1C) levels in patients of Type 2 diabetes mellitus controlled with diet, exercise and oral hypoglycemic agents (OHAs) or insulin.
Aims: Assessment of impact of ingestion of Trigonella foenum-graecum or fenugreek seed in patients with Type 2 diabetes controlled with OHAs and insulin on fasting blood sugar levels and HbA1C levels.
Settings and design: Prospective, randomized control trial in a single center.
Materials and methods: Total sixty patients of Type 2 diabetes mellitus diagnosed at least 6 months prior and on OHAs and insulin were included in the study. Patients were randomized to receive 10 gm of fenugreek seeds soaked in hot water and another group was not. Strict dietary and exercise controls were followed as per the guidelines of American Diabetic Association protocols. The parameters assessed were demographic profile on the first visits and fasting blood sugar levels and HbA1C every month till 6 months.
Results: A total of sixty patients were enrolled in the study divided into two groups each containing thirty patients. One group of patients received 10 gm of fenugreek seeds soaked in hot water every day, while the second group did not received. Statistical analysis shows that there is significant reduction in fasting blood glucose levels in the 5th month in the study group (P = 0.0421) while significant reduction in HbA1C in the 6th month (P = 0.0201).
Conclusion: A simple complementary addition of fenugreek seeds can have a synergistic effect along with diet control and exercise on fasting blood glucose and HbA1c but is of delayed occurrence.
Keywords: Fasting blood glucose; fenugreek seeds; glycosylated hemoglobin (HbA1C); type 2 diabetes.