Dietary Fermentable Oligosaccharides, Disaccharides, Monosaccharides, and Polyols (FODMAPs) and Gastrointestinal Disease

Nutr Clin Pract. 2018 Aug;33(4):468-475. doi: 10.1002/ncp.10108. Epub 2018 Jun 5.

Abstract

FODMAP is an acronym for fermentable oligosaccharides, disaccharides, monosaccharides, and polyols. Dietary modification of FODMAPs has been shown to have significant effects on the physiology of the gastrointestinal tract and improves symptoms of abdominal pain, distention, and bloating in patients with irritable bowel syndrome. Structured withdrawal and reintroduction of FODMAPs supervised by a dietitian is the optimal practice for dietary FODMAP modification in irritable bowel syndrome. FODMAPs are present in enteral feeding formulas and may have a role in diarrhea and bloating in tube-fed patients. Emerging areas of research include the effects of dietary modification of FODMAPs on the microbiome, micronutrient absorption, and caloric intake. FODMAP dietary modification is an emerging area in other gastrointestinal disorders and is of relevance to all practicing dietitians.

Keywords: FODMAP; disaccharides; enteral nutrition; inflammatory bowel diseases; irritable bowel syndrome; microbiota; monosacccharides; oligosaccharides; polysaccharides; sugar alcohols.

Publication types

  • Review

MeSH terms

  • Diet*
  • Dietary Carbohydrates
  • Disaccharides / adverse effects
  • Energy Intake / drug effects
  • Enteral Nutrition
  • Feeding Behavior*
  • Fermentation*
  • Gastrointestinal Diseases / diet therapy
  • Gastrointestinal Diseases / pathology
  • Gastrointestinal Microbiome / drug effects
  • Humans
  • Intestinal Absorption / drug effects
  • Irritable Bowel Syndrome / diet therapy*
  • Irritable Bowel Syndrome / pathology
  • Monosaccharides / adverse effects*
  • Oligosaccharides / adverse effects*
  • Polymers / adverse effects*

Substances

  • Dietary Carbohydrates
  • Disaccharides
  • Monosaccharides
  • Oligosaccharides
  • Polymers
  • polyol