Severe and persistent morphine-induced respiratory depression associated with ATP-Binding Cassette Subfamily B Member 1 and catechol-O-methyltransferase genetic defects: A case report

Eur J Anaesthesiol. 2018 Jul;35(7):540-542. doi: 10.1097/EJA.0000000000000801.

Authors

Gaspard Aebischer¹, Kuntheavy Ing Lorenzini, Simon Tomala, Jules Desmeules, Youssef Daali, Caroline F Samer

Affiliation

¹ From the Division of General Internal Medicine (GA), Division of Clinical Pharmacology and Toxicology (RIK, JD, YD, CS) and Division of Anaesthesiology, Geneva University Hospitals, Geneva, Switzerland (ST).

PMID: 29870475
DOI: 10.1097/EJA.0000000000000801

No abstract available

Publication types

Case Reports
Letter

MeSH terms

ATP Binding Cassette Transporter, Subfamily B / genetics
Aged
Analgesics, Opioid / adverse effects*
Catechol O-Methyltransferase / genetics*
Female
Humans
Morphine / adverse effects*
Respiratory Insufficiency / chemically induced*
Respiratory Insufficiency / diagnosis
Respiratory Insufficiency / genetics*
Severity of Illness Index

Substances

ABCB1 protein, human
ATP Binding Cassette Transporter, Subfamily B
Analgesics, Opioid
Morphine
COMT protein, human
Catechol O-Methyltransferase