[Giant cell reparative granuloma originating from the paranasal sinus: a case report]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Feb 5;31(3):233-234. doi: 10.13201/j.issn.1001-1781.2017.03.017.
[Article in Chinese]


A 40-year-old man presented with a 10-year history of nasal obstruction of his left nose, a 1-year history of headache and orbital pain. Radiologically, an extensive paranasal sinus mass was seen. Superiorly ,the cribriform plate was demineralized, and the lesion had intracranial extension with mild mass effect over the basal frontal lobes. Histologic examination revealed a central giant cell reparative granuloma. After endoscopic removal, the patient was symptom free at the 2-month follow-up.

Keywords: giant cell; granuloma; paranasal sinus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Endoscopy*
  • Ethmoid Bone / pathology
  • Ethmoid Bone / surgery
  • Giant Cells
  • Granuloma, Giant Cell / diagnosis*
  • Granuloma, Giant Cell / pathology
  • Granuloma, Giant Cell / surgery
  • Humans
  • Male
  • Nasal Obstruction / etiology*
  • Nasal Obstruction / surgery
  • Nose Neoplasms / diagnosis*
  • Nose Neoplasms / pathology
  • Nose Neoplasms / surgery
  • Paranasal Sinus Diseases / diagnosis*
  • Paranasal Sinus Diseases / pathology
  • Paranasal Sinus Diseases / surgery
  • Paranasal Sinuses / pathology