[Progressive Renal Insufficiency in a 55-year-old Man With Psoriasis]

Internist (Berl). 2018 Nov;59(11):1204-1207. doi: 10.1007/s00108-018-0446-x.
[Article in German]


Treatment with tumor necrosis factor alpha (TNF-α) inhibitors is a well-established therapeutic strategy for various autoimmune diseases. However, little is known about renal complications and possible causality of renal injury due to this treatment. The following case of a patient with psoriasis demonstrates the difficulties in classifying renal complications of anti-TNF-α therapy versus kidney involvement caused by the underlying disease.

Keywords: Adalimumab; IgA glomerulonephritis; Prednisolone; Tumor necrosis factor-α inhibitors; Ustekinumab.

Publication types

  • Case Reports

MeSH terms

  • Adalimumab / therapeutic use*
  • Glomerulonephritis, IGA
  • Humans
  • Infliximab
  • Male
  • Middle Aged
  • Psoriasis / drug therapy*
  • Renal Insufficiency / chemically induced*
  • Tumor Necrosis Factor-alpha / antagonists & inhibitors
  • Tumor Necrosis Factor-alpha / therapeutic use*
  • Ustekinumab / therapeutic use*


  • Tumor Necrosis Factor-alpha
  • Infliximab
  • Ustekinumab
  • Adalimumab