Prediction of survival in glioma patients by means of positron emission tomography

J Neurosurg. 1985 Jun;62(6):816-22. doi: 10.3171/jns.1985.62.6.0816.


The aim of this study was to determine whether positron emission tomography (PET) with fluorine-18 (18F)-2-deoxyglucose (FDG) can be used as a prognostic test in patients with high-grade cerebral gliomas, regardless of the treatment given. Forty-five patients with astrocytoma Grade III or IV were included in this analysis. The mean survival time of patients with tumors exhibiting high glucose utilization as determined by PET-FDG was 5 months, whereas patients with gliomas showing lower glucose utilization had a mean survival period of 19 months. It is postulated that PET-FDG scans reflect the biological behavior of high-grade astrocytomas and may be used to predict the survival time of patients harboring such neoplasms.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Brain Neoplasms / diagnostic imaging*
  • Brain Neoplasms / mortality
  • Deoxyglucose / analogs & derivatives
  • Female
  • Fluorine
  • Fluorodeoxyglucose F18
  • Glioblastoma / diagnostic imaging*
  • Glioblastoma / mortality
  • Humans
  • Male
  • Middle Aged
  • Radiography
  • Radioisotopes
  • Tomography, Emission-Computed*


  • Radioisotopes
  • Fluorodeoxyglucose F18
  • Fluorine
  • Deoxyglucose