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, 9 (2), 276-282

Remineralizing Effectiveness of Calcium Sucrose Phosphate and Fluoride Dentifrices: An In vitro Study

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Remineralizing Effectiveness of Calcium Sucrose Phosphate and Fluoride Dentifrices: An In vitro Study

Tinsy Mary Titty et al. Contemp Clin Dent.

Abstract

Context: Dentifrices-containing remineralizing agents are known to be effective in remineralization of early enamel lesions.

Aims: This study aimed to compare and evaluate the changes in surface roughness, surface morphology, and mineral content of demineralized enamel lesion after treatment with dentifrices-containing sodium monofluorophosphate, amine fluoride, and Anticay® (calcium sucrose phosphate with inorganic amorphous calcium phosphate).

Settings and design: This was an in vitro study.

Subjects and methods: Eighteen extracted maxillary molars were decoronated and sectioned into four to obtain 72 specimens. Specimens were demineralized and randomly divided into four different test groups: Group A: no treatment (control), Group B: sodium monofluorophosphate dentifrice (Colgate), Group C: amine fluoride dentifrice (Amflor), Group D: Anticay® dentifrice (EnaFix) and subjected to pH-cycling for 4 weeks. After 4 weeks, they were assessed using a profilometer and scanning electron microscope (SEM)-energy dispersive X-ray analysis (EDAX) for changes in surface roughness, surface morphology, and mineral content.

Statistical analysis used: Intergroup comparison was done using repeated measures ANOVA.

Results: Intergroup comparison revealed no significant difference in surface roughness and mineral content after remineralization between the groups. SEM images showed mineral deposition in all the dentifrice groups obliterating the defects caused due to demineralization.

Conclusions: Sodium monofluorophosphate, amine fluoride-containing dentifrices, and calcium sucrose phosphate with inorganic amorphous calcium phosphate-containing dentifrice were found equivocal in their remineralizing effectiveness of early enamel lesions.

Keywords: Calcium sucrose phosphate; dentifrice; fluoride; remineralization.

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Scanning electron microscope image (at ×2000 magnification) depicting the surface morphology of the demineralized enamel
Figure 2
Figure 2
Scanning electron microscope image (at ×2000 magnification) depicting the surface morphology of the enamel of the control group after 4-week remineralization
Figure 3
Figure 3
Scanning electron microscope image (at ×2000 magnification) depicting the surface morphology of the enamel of the sodium monofluorophosphate group after 4-week remineralization
Figure 4
Figure 4
Scanning electron microscope image (at ×2000 magnification) depicting the surface morphology of the enamel of the amine fluoride group after 4-week remineralization
Figure 5
Figure 5
Scanning electron microscope image (at ×2000 magnification) depicting the surface morphology of the enamel of the Anticay® group after 4-week remineralization

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References

    1. Featherstone JD. Dental caries: A dynamic disease process. Aust Dent J. 2008;53:286–91. - PubMed
    1. ten Cate JM. Current concepts on the theories of the mechanism of action of fluoride. Acta Odontol Scand. 1999;57:325–9. - PubMed
    1. Toda S, Featherstone JD. Effects of fluoride dentifrices on enamel lesion formation. J Dent Res. 2008;87:224–7. - PubMed
    1. Ekambaram M, Itthagarun A, King NM. Comparison of the remineralizing potential of child formula dentifrices. Int J Paediatr Dent. 2011;21:132–40. - PubMed
    1. Gangrade A, Gade V, Patil S, Gade J, Chandhok D, Thakur D. In vitro evaluation of remineralization efficacy of different calcium and fluoride-based delivery systems on artificially demineralized enamel surface. J Conserv Dent. 2016;19:328–31. - PMC - PubMed
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