Context: Dentifrices-containing remineralizing agents are known to be effective in remineralization of early enamel lesions.
Aims: This study aimed to compare and evaluate the changes in surface roughness, surface morphology, and mineral content of demineralized enamel lesion after treatment with dentifrices-containing sodium monofluorophosphate, amine fluoride, and Anticay® (calcium sucrose phosphate with inorganic amorphous calcium phosphate).
Settings and design: This was an in vitro study.
Subjects and methods: Eighteen extracted maxillary molars were decoronated and sectioned into four to obtain 72 specimens. Specimens were demineralized and randomly divided into four different test groups: Group A: no treatment (control), Group B: sodium monofluorophosphate dentifrice (Colgate), Group C: amine fluoride dentifrice (Amflor), Group D: Anticay® dentifrice (EnaFix) and subjected to pH-cycling for 4 weeks. After 4 weeks, they were assessed using a profilometer and scanning electron microscope (SEM)-energy dispersive X-ray analysis (EDAX) for changes in surface roughness, surface morphology, and mineral content.
Statistical analysis used: Intergroup comparison was done using repeated measures ANOVA.
Results: Intergroup comparison revealed no significant difference in surface roughness and mineral content after remineralization between the groups. SEM images showed mineral deposition in all the dentifrice groups obliterating the defects caused due to demineralization.
Conclusions: Sodium monofluorophosphate, amine fluoride-containing dentifrices, and calcium sucrose phosphate with inorganic amorphous calcium phosphate-containing dentifrice were found equivocal in their remineralizing effectiveness of early enamel lesions.
Keywords: Calcium sucrose phosphate; dentifrice; fluoride; remineralization.
Conflict of interest statement
There are no conflicts of interest.
Surface Remineralization Potential of Nano-Hydroxyapatite, Sodium Monofluorophosphate, and Amine Fluoride Containing Dentifrices on Primary and Permanent Enamel Surfaces: An in vitro StudyN Grewal et al. J Indian Soc Pedod Prev Dent 36 (2), 158-166. PMID 29970633.Nano-hydroxyapatite exhibited highest remineralization potential in terms of mineral gain followed by amine fluoride and sodium monofluorophosphate dentifrice.
In Situ Clinical Effects of New Dentifrices Containing 1.5% Arginine and Fluoride on Enamel De- And Remineralization and Plaque MetabolismR Cantore et al. J Clin Dent 24 Spec no A, A32-44. PMID 24156138. - Randomized Controlled TrialIn Study 1, the percent mineral changes were +18.64, +16.77, +4.08, and -24.95 for the 1.5% arginine/Dical/1450 ppm fluoride, the 1.5% arginine/calcium carbonate/1450 ppm …
Comparative Evaluation of the Remineralization Potential of Monofluorophosphate, Casein Phosphopeptide-Amorphous Calcium Phosphate and Calcium Sodium Phosphosilicate on Demineralized Enamel Lesions: An In Vitro StudyK Kumar et al. Cureus 10 (7), e3059. PMID 30280056.The results of this study suggest that, among the three agents tested, calcium sodium phosphosilicate is the most effective remineralizing agent followed by casein phosph …
Effects of Regular and Whitening Dentifrices on Remineralization of Bovine Enamel in VitroAM Kielbassa et al. Quintessence Int 40 (2), 103-12. PMID 19169441.Dentifrices containing pyrophosphates perform worse than regular dentifrices but do not necessarily affect remineralization. Unless remineralizing efficacy is proven, whi …
Comparative Evaluation of Remineralizing Potential of Three Pediatric DentifricesA Kapoor et al. Int J Clin Pediatr Dent 9 (3), 186-191. PMID 27843247. - ReviewOne can use pediatric dentifrices for preventing dental caries and decelerating lesion progression with an added advantage of lower fluoride toxicity risk.
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