Leading the charge

Elife. 2018 Jun 7:7:e37910. doi: 10.7554/eLife.37910.

Abstract

A simple label-free method uses the electrical properties of cells to detect how ligands bind to membrane proteins.

Keywords: cocaine; electrophysiology; human; human serotonin transporter; membrane capacitance; molecular biophysics; serotonin; structural biology; surface charge.

Publication types

  • Comment

MeSH terms

  • Biophysical Phenomena*
  • Ligands
  • Membrane Glycoproteins
  • Membrane Proteins*
  • Membrane Transport Proteins
  • Serotonin Plasma Membrane Transport Proteins

Substances

  • Ligands
  • Membrane Glycoproteins
  • Membrane Proteins
  • Membrane Transport Proteins
  • Serotonin Plasma Membrane Transport Proteins