Abstract
We discuss a recent study that has identified and validated the link between a type-2 diabetes (T2D) association and human adipose biology by means of KLF14 gene expression. In addition to being maternally imprinted, the contributed risk at this locus is greater in female carriers.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Adiposity / genetics*
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Animals
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Diabetes Mellitus, Type 2 / genetics
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Gene Expression
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Genetic Loci / genetics*
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Genetic Predisposition to Disease / genetics*
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Genome-Wide Association Study / methods
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Genomics / methods
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Humans
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Sp Transcription Factors / genetics