Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jun 6;8(6):e021808.
doi: 10.1136/bmjopen-2018-021808.

Cohort Profile: The Coronary Artery Disease Risk Determination In Innsbruck by diaGnostic ANgiography (CARDIIGAN) Cohort

Free PMC article

Cohort Profile: The Coronary Artery Disease Risk Determination In Innsbruck by diaGnostic ANgiography (CARDIIGAN) Cohort

Maria Wanitschek et al. BMJ Open. .
Free PMC article


Purpose: The Coronary Artery disease Risk Determination In Innsbruck by diaGnostic ANgiography (CARDIIGAN) cohort is aimed to gain a better understanding of cardiovascular risk factors and their relation to the diagnosis and severity of coronary artery disease, as well as to the long-term prognosis in consecutive (including revascularised) patients referred for elective coronary angiography.

Participants: The included patients visited the University Clinic of Cardiology at Innsbruck (Austria), which fulfils a secondary and tertiary hospital function. Inclusion took place in the period between February 2004 and April 2008 and resulted in a total of 8296 patients aged 18-91 years; 65% of them were men.

Findings to date: There was one follow-up round on vital status through record linkage for 84% of the cohort (those with residence in Tyrol), resulting in a follow-up duration of over 5.5 to nearly 10.0 years among survivors. The data contain basic patient characteristics, cardiovascular risk factors, laboratory measurements, medications, detailed information on the extent and severity of coronary artery disease, revascularisation history, treatment strategy and mortality specifics. A few studies have already been published.

Future plans: Various diagnostic and prognostic studies are planned, also concerning complications, competing risks and cost-effectiveness. Collaboration with other research groups is welcomed.

Keywords: cardiovascular risk factors; clinical epidemiology; cohort study; coronary artery disease; elective cardiac catheterisation.

Conflict of interest statement

Competing interests: None declared.


Figure 1
Figure 1
Subgroups of the CARDIIGAN cohort. The term ‘local’ indicates that survival data are available from the regional social security system. CABG, coronary artery bypass grafting; CAD, coronary artery disease; CARDIIGAN, Coronary Artery disease Risk Determination In Innsbruck by diaGnostic ANgiography; PCI, percutaneous coronary intervention.

Similar articles

See all similar articles


    1. WHO. Health statistics and information systems. (accessed 14 Oct 2016).
    1. Statistics Austria. Todesursachen gesamt. (accessed 14 Oct 2016).
    1. Chen G, Levy D. Contributions of the Framingham Heart Study to the epidemiology of coronary heart disease. JAMA Cardiol 2016;1:825–30. 10.1001/jamacardio.2016.2050 - DOI - PubMed
    1. Oberaigner W, Stühlinger W. Record linkage in the cancer registry of Tyrol, Austria. Methods Inf Med 2005;44:626–30. - PubMed
    1. Oberaigner W. Errors in survival rates caused by routinely used deterministic record linkage methods. Methods Inf Med 2007;46:420–4. - PubMed