Continuous Visible-Light Photoflow Approach for a Manganese-Catalyzed (Het)Arene C-H Arylation

Yu-Feng Liang; Ralf Steinbock; Long Yang; Lutz Ackermann

doi:10.1002/anie.201805644

Continuous Visible-Light Photoflow Approach for a Manganese-Catalyzed (Het)Arene C-H Arylation

Angew Chem Int Ed Engl. 2018 Aug 13;57(33):10625-10629. doi: 10.1002/anie.201805644. Epub 2018 Jul 3.

Authors

Yu-Feng Liang¹, Ralf Steinbock¹, Long Yang¹, Lutz Ackermann¹

Affiliation

¹ Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstraße 2, 37077, Göttingen, Germany.

PMID: 29882633
DOI: 10.1002/anie.201805644

Abstract

Manganese photocatalysts enabled versatile room-temperature C-H arylation reactions by means of continuous visible-light photoflow, thus allowing for efficient C-H arylations in 30 minutes with ample scope. The robustness of the manganese-catalyzed photoflow strategy was shown by visible light-induced gram-scale synthesis, clearly outperforming the batch performance.

Keywords: C−H arylations; continuous photoflow reactions; manganese; photocatalysis; visible light.