Insulin decreases expression of the proinflammatory receptor proteinase-activated receptor-2 on human airway epithelial cells

J Allergy Clin Immunol. 2018 Sep;142(3):1003-1006.e8. doi: 10.1016/j.jaci.2018.04.040. Epub 2018 Jun 8.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Asthma / metabolism
  • Bronchi / cytology
  • Cells, Cultured
  • Diet, High-Fat
  • Epithelial Cells / drug effects*
  • Epithelial Cells / metabolism
  • Humans
  • Insulin / pharmacology*
  • Lung / drug effects*
  • Lung / metabolism
  • Male
  • Mice, Inbred C57BL
  • Receptor, PAR-2 / genetics
  • Receptor, PAR-2 / metabolism*

Substances

  • Insulin
  • Receptor, PAR-2

Grants and funding