Risk factors and etiopathogenesis of potentially premalignant oral epithelial lesions

Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 Jun;125(6):603-611. doi: 10.1016/j.oooo.2018.03.008. Epub 2018 Mar 20.

Abstract

Potentially malignant oral mucosal disease has some ability to give rise to malignancy of the oral epithelium, that is, oral squamous cell carcinoma (OSCC). The present article provides a succinct review of the possible or probable causes of potentially premalignant oral epithelial lesions. There is a focus upon studies that examined the causes or etiologic associations with clinically likely or histopathologically detectable oral epithelial dysplasia.

Publication types

  • Review

MeSH terms

  • Carcinoma, Squamous Cell / etiology*
  • Carcinoma, Squamous Cell / pathology*
  • Cell Transformation, Neoplastic / pathology*
  • Diagnosis, Oral
  • Disease Progression
  • Erythroplasia / pathology*
  • Humans
  • Leukoplakia, Oral / pathology*
  • Mouth Neoplasms / etiology*
  • Mouth Neoplasms / pathology*
  • Precancerous Conditions / pathology*
  • Risk Factors