Bioactive Fibers: Hydrogel Templates for Rapid Manufacturing of Bioactive Fibers and 3D Constructs (Adv. Healthcare Mater. 14/2015)

Ali Tamayol; Alireza Hassani Najafabadi; Bahar Aliakbarian; Elmira Arab-Tehrany; Mohsen Akbari; Nasim Annabi; David Juncker; Ali Khademhosseini

doi:10.1002/adhm.201570082

Bioactive Fibers: Hydrogel Templates for Rapid Manufacturing of Bioactive Fibers and 3D Constructs (Adv. Healthcare Mater. 14/2015)

Adv Healthc Mater. 2015 Oct;4(14):2050. doi: 10.1002/adhm.201570082.

Authors

Ali Tamayol^{1

2}, Alireza Hassani Najafabadi^{1

2}, Bahar Aliakbarian^{1

2}, Elmira Arab-Tehrany^{1

2}, Mohsen Akbari^{1

2

3}, Nasim Annabi^{1

2

3}, David Juncker^{4

5

6}, Ali Khademhosseini^{1

2

3

7}

Affiliations

¹ Biomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.
² Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
³ Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, 02115, USA.
⁴ Department of Biomedical Engineering, McGill University and Genome Quebec Innovation Centre, McGill University, Montreal, H3A 0G1, Canada.
⁵ McGill University and Genome Quebec Innovation Centre, Montreal, H3A 2B4, Canada.
⁶ Department of Neurology and Neurosurgery, McGill University, Montreal, H3A 0G1, Canada.
⁷ Department of Physics, King Abdulaziz University, Jeddah, 21569, Saudi Arabia.

PMID: 29896903
DOI: 10.1002/adhm.201570082

Abstract

Hybrid hydrogel fibers were fabricated using hydrogel templates. On page 2146, D. Juncker, A. Khademhosseini, and co-workers show how these fibers containing different fluorescent microbeads have been assembled using textile processes, such as braiding and weaving, to create complex 3D patterns for bioengineering applications. The fabricated constructs with clinically relevant dimensions are mechanically stable.

Keywords: bioprinting; cell-laden fibers; fiber-based methods; sacrificial polymeric networks; tissue engineering.