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Role of the Gut Microbiota in Nutrition and Health


Role of the Gut Microbiota in Nutrition and Health

Ana M Valdes et al. BMJ.


Ana M Valdes and colleagues discuss strategies for modulating the gut microbiota through diet and probiotics

Conflict of interest statement

Competing interests: We have read and understood BMJ policy on competing interests and declare the following: AMV and TS are consultants to Zoe Global. JW has received research funding from industry sources involved in the manufacture and marketing of prebiotics and dietary fibres and is a co-owner of Synbiotics Solutions, a developer of synbiotic products. ES is a consultant of DayTwo Inc. AMV is funded by the NIHR Nottingham Biomedical Research Centre. JW is supported through the Campus Alberta Innovates programme and grants of the Canadian Institute of Health Research (CIHR), Natural Sciences and Engineering Research Council of Canada (NSERC), the JPI HDHL, and the Canadian Foundation for Innovation. ES is supported by the Crown Human Genome Center; the Else Kroener Fresenius Foundation; Donald L. Schwarz, Sherman Oaks, CA; Jack N Halpern, New York, NY; Leesa Steinberg, Canada; and grants funded by the European Research Council and the Israel Science Foundation. TwinsUK was funded by the Wellcome Trust; European Community’s Seventh Framework Programme (FP7/2007-2013). The study also receives support from the National Institute for Health Research (NIHR) BioResource Clinical Research Facility and Biomedical Research Centre based at Guy’s and St Thomas’ NHS Foundation Trust and King’s College London. TDS is an NIHR senior investigator.


Fig 1
Fig 1
Schematic representation of the role of the gut microbiota in health and disease giving some examples of inputs and outputs. CVD=cardiovascular disease; IPA=indolepropionic acid; LPS=lipopolysaccharide; SCFA=short chain fatty acids; TMAO=trimethylamine N-oxide

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