Data from a targeted proteomics approach to discover biomarkers in saliva for the clinical diagnosis of periodontitis

Data Brief. 2018 Mar 12;18:294-299. doi: 10.1016/j.dib.2018.03.036. eCollection 2018 Jun.


This study focused on the search for new biomarkers based on liquid chromatography-multiple reaction monitoring (LC-MRM) proteomics profiling of whole saliva from patients with periodontitis compared to healthy subjects. The LC-MRM profiling approach is a new and innovative method that has already been validated for the absolute and multiplexed quantification of biomarkers in several diseases. The dataset for this study was produced using LC-MRM to monitor protein levels in a multiplex assay, it provides clinical information on salivary biomarkers of periodontitis. The data presented here is an extension of our recently published research article (Mertens et al., 2017) [1].

Keywords: Clinical chemistry; Mass spectrometry; Oral disease; Periodontitis; Proteomics; Saliva biochemistry.