Human papillomavirus type 16 DNA sequence

Virology. 1985 Aug;145(1):181-5. doi: 10.1016/0042-6822(85)90214-4.


The complete nucleotide sequence of HPV16 DNA (7904 bp) cloned from an invasive cervical carcinoma was determined. Homology comparisons allowed us to align the major open reading frames with the other published papilloma virus DNA sequences. The general organization of the open reading frames is similar to that of the other four papillomavirus (BPV1, HPV1a, HPV6b, CRPV) already sequenced. The sequence reveals an interruption of the reading frame coding for a suspected E1 protein.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Cloning, Molecular
  • Codon
  • DNA Restriction Enzymes
  • DNA, Viral* / genetics
  • Humans
  • Papillomaviridae / genetics*
  • Protein Biosynthesis
  • Viral Proteins / genetics


  • Codon
  • DNA, Viral
  • Viral Proteins
  • DNA Restriction Enzymes

Associated data

  • GENBANK/K02718