HIV Env on Lockdown

Cell Host Microbe. 2018 Jun 13;23(6):699-701. doi: 10.1016/j.chom.2018.05.017.

Abstract

No immunogen has been found that elicits a broadly neutralizing antibody (bNAb) response sufficient for development into an HIV vaccine. In this issue of Cell Host and Microbe, Zhang et al. (2018) rationally design an HIV envelope glycoprotein variant that provides new hope that such an immunogen may be attainable.

Publication types

  • Comment

MeSH terms

  • AIDS Vaccines
  • Antibodies, Neutralizing
  • Epitopes
  • HIV Antibodies*
  • HIV Envelope Protein gp120
  • HIV Infections
  • HIV-1 / immunology
  • Humans
  • env Gene Products, Human Immunodeficiency Virus*

Substances

  • AIDS Vaccines
  • Antibodies, Neutralizing
  • Epitopes
  • HIV Antibodies
  • HIV Envelope Protein gp120
  • env Gene Products, Human Immunodeficiency Virus