Objective: To establish a method for detecting 21 semi-volatile organic compounds in the source of drinking water by gas chromatography triple quadruples mass spectrometry( GC-MS/MS).
Methods: To process multiple samples at the same time, using large volume solid-phase extraction device for continuous injection. The water samples were extracted by C_(18) solid phase column, eluted with methylene chloride and ethylacetate, and then separated by DB-5MS capillary column. The target substance in the extractions was selected by gas chromatography triple quadruples spectrometry in selectedreaction monitoring( SRM) mode. Retention time and selected ions were used for qualitative analysis, acenaphthene-d_(10), phenanthrene-d_(10) and chrysene-d_(12) were used as internal standard for qualitative analysis of 21 semi-volatile organic compounds.
Results: The method was good sensitivity, stability and high selectivity, which could improve the sensitivity of target compounds by secondary mass spectrum scanning through reducing the background interference. The separate rates of 21 kinds of compounds were well, and the correlation coefficients were more than 0. 9902. The minimum detection concentration was 5. 0 × 10~(-5)mg/L, the average recovery rates were 72. 6%-127. 3% and the relativestandard deviation were 1. 05%-9. 89%.
Conclusion: This method is simple, rapid with high accuracy and reliable, so it is suitable for detecting semi-volatile organic compounds in water.
Keywords: drinking water; gas chromatography triple quadruples mass spectrometry; semi-volatile organic compounds.