Nuclear Medicine Imaging in the Dentomaxillofacial Region

Dent Clin North Am. 2018 Jul;62(3):491-509. doi: 10.1016/j.cden.2018.03.008.


Nuclear medicine studies evaluate physiology on a molecular level providing earlier detection of lesions before morphologic change is evident. 99mTc-MDP and 18F-fluoride bone scans detect osteomyelitis earlier than radiographs and computed tomography (CT); aid in diagnosis of temporomandibular joint disorder; and evaluate activity of condylar hyperplasia, extent of Paget disease, and viability of bone grafts. 18F-FDG PET/CT distinguish between soft tissue and bone infections and diagnose osteomyelitis complicated by fracture or surgery. FDG PET is more accurate than CT alone and has a major role in staging, restaging, and assessing response to therapy for head and neck malignancies and in detecting sequelae of therapy.

Keywords: (18)F sodium fluoride bone scan; (18)F-FDG; (99m)Tc-MDP; Condylar hyperplasia; Dentomaxillofacial; Nuclear medicine; Osteomyelitis; Temporomandibular disorder.

Publication types

  • Review

MeSH terms

  • Acquired Hyperostosis Syndrome / diagnostic imaging
  • Bone Neoplasms / diagnostic imaging
  • Face / diagnostic imaging*
  • Fluorodeoxyglucose F18
  • Head and Neck Neoplasms / diagnostic imaging
  • Humans
  • Hyperplasia / diagnostic imaging
  • Infections / diagnostic imaging
  • Mandibular Condyle / diagnostic imaging
  • Mandibular Condyle / pathology
  • Maxilla / diagnostic imaging*
  • Osteitis Deformans / diagnostic imaging
  • Periodontitis / diagnostic imaging
  • Positron Emission Tomography Computed Tomography*
  • Positron-Emission Tomography*
  • Radiopharmaceuticals
  • Sjogren's Syndrome / diagnostic imaging
  • Technetium Tc 99m Medronate
  • Technology, Dental
  • Temporomandibular Joint Disorders / diagnostic imaging
  • Tomography, X-Ray Computed


  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18
  • Technetium Tc 99m Medronate