A rare case of 40-years-old women presented with yellow-white and clear yellow mucous vaginal discharge, foul smell and itching per vagina 7 months ago. She had pleuritic chest pain and amenorrhea for 2 years. The cervix revealed a hyperemic, irregular in outline, ulcerated, and contact bleeding that similar to cervical cancer. The colposcopic examination showed acetowhite epithelium. Cervical biopsy revealed granulomatous inflammation. Cervical tissue culture was Mycobacterial tuberculosis. Standard anti-tuberculotic drugs treated patient’s disease for 6 months. The abnormal vaginal discharge, cervical lesion and chest pain were resolved. Tuberculosis should be an important differential diagnosis of the malignantappearing cervical lesion in the area that high prevalence of disease, especially Thailand.