Infection and recurrence rates of the C-QUR V-Patch in ventral hernia repairs

Hernia. 2018 Oct;22(5):767-772. doi: 10.1007/s10029-018-1791-3. Epub 2018 Jun 15.

Abstract

Purpose: Ventral hernias are a common surgical issue and a myriad of surgical mesh designs has been developed for their treatment. Many of these new mesh designs have not been extensively tested and their complications rates are largely unknown. The C-QUR V-Patch Mesh combines a unique knit construction polypropylene mesh with an omega-3 fatty acid coating. There has only previously been one reported study investigating this mesh.

Methods: A multicentre cohort study, with a single surgeon, of 168 consecutive patients with ventral hernias underwent repair using a standardized open pre-peritoneal approach with the novel C-QUR V-Patch Mesh between January 2013 and June 2015. A median follow-up of 37 months was completed to assess the patients for hernia infection and recurrence rates. Mesh infections were further classified into early and late infections for further subgroup analysis.

Results: Infection and recurrence rates of the C-QUR V-Patch® were compared with similar published results of alternate mesh designs. Surgical site infection rates were 7.7% and recurrence rates were 2.4%. The infection rate rose dramatically to 19.0% when the mesh was placed intra-peritoneally. The rate of mesh explantation was 2.4% and usually occurred between 4 and 12 months post-operatively. Smoking was the only factor that appeared to be associated with recurrence.

Conclusion: This series finds that recurrence rates associated with the novel C-QUR V-Patch Mesh is acceptably low; however, infection rates appear to be higher when compared to comparable products for use in ventral hernia repairs.

Keywords: Mesh; Umbilical hernia; Ventral hernia.

Publication types

  • Multicenter Study
  • Observational Study

MeSH terms

  • Aged
  • Australia / epidemiology
  • Coated Materials, Biocompatible
  • Cohort Studies
  • Fatty Acids, Omega-3 / administration & dosage
  • Female
  • Hernia, Ventral / surgery*
  • Humans
  • Male
  • Middle Aged
  • Polypropylenes
  • Recurrence
  • Smoking / adverse effects
  • Surgical Mesh*
  • Surgical Wound Infection / epidemiology*

Substances

  • Coated Materials, Biocompatible
  • Fatty Acids, Omega-3
  • Polypropylenes