Abstract
Three new sulfated isoguanine alkaloid glycosides, designated as saikachinoside A monosulfate (1), saikachinoside A disulfate (2), and locustoside B disulfate (3), have been isolated from the pupal case of the wild bruchid seed beetle Bruchidius dorsalis (Chrysomelidae, Bruchinae) infesting the seed of Gleditsia japonica Miq. (Fabaceae). Their structures were determined by spectroscopic methods and the inhibitory activity of 2 and 3 against acid phosphatase was evaluated.
Keywords:
Bruchidius dorsalis; Gleditsia japonica; bruchid seed beetle; pupal case; sulfated purine alkaloid.
© 2018 Wiley-VHCA AG, Zurich, Switzerland.
MeSH terms
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Acid Phosphatase / antagonists & inhibitors
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Acid Phosphatase / metabolism
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Alkaloids / chemistry
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Alkaloids / isolation & purification
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Alkaloids / pharmacology*
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Animals
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Coleoptera / chemistry*
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Dose-Response Relationship, Drug
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Enzyme Inhibitors / chemistry
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Enzyme Inhibitors / isolation & purification
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Enzyme Inhibitors / pharmacology
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Gleditsia / chemistry*
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Glycosides / chemistry
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Glycosides / isolation & purification
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Glycosides / pharmacology*
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Molecular Conformation
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Pupa / chemistry
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Purines / chemistry
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Purines / isolation & purification
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Purines / pharmacology*
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Seeds / chemistry*
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Structure-Activity Relationship
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Sulfates / chemistry
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Triticum / enzymology
Substances
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Alkaloids
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Enzyme Inhibitors
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Glycosides
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Purines
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Sulfates
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Acid Phosphatase
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purine