Primary thyroid angiosarcoma: A systematic review

F De Felice; E Moscatelli; S Orelli; N Bulzonetti; D Musio; V Tombolini

doi:10.1016/j.oraloncology.2018.05.004

Primary thyroid angiosarcoma: A systematic review

Oral Oncol. 2018 Jul:82:48-52. doi: 10.1016/j.oraloncology.2018.05.004. Epub 2018 May 11.

Authors

F De Felice¹, E Moscatelli², S Orelli³, N Bulzonetti⁴, D Musio⁵, V Tombolini⁶

Affiliations

¹ Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy. Electronic address: fradefelice@hotmail.it.
² Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy. Electronic address: erika.moscatelli@uniroma1.it.
³ Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy. Electronic address: simone.orelli@uniroma1.it.
⁴ Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy. Electronic address: nadia.bulzonetti@uniroma1.it.
⁵ Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy. Electronic address: danela.musio@uniroma1.it.
⁶ Department of Radiotherapy, Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy. Electronic address: vincenzo.tombolini@uniroma1.it.

PMID: 29909901
DOI: 10.1016/j.oraloncology.2018.05.004

Abstract

Thyroid angiosarcoma (TAS) is rare and represents a very aggressive malignancy. Its rarity is principally linked to two major pitfalls. Firstly, TAS histopathology diagnosis can be difficult; second, the limited clinical experience with this condition can make its management complex. We conducted a detailed systematic review, focusing on the knowledge available regarding TAS etiopathogenesis, treatment options and prognosis. The aim is to present the main TAS characteristics and to summarize the clinical experiences described worldwide, in order to provide a useful clinical tool.

Keywords: Angiosarcoma; Chemotherapy; Radiotherapy; Sarcoma; Surgery; Therapy; Thyroid; Treatment.

Publication types

Systematic Review

MeSH terms

Early Detection of Cancer
Hemangiosarcoma / diagnosis*
Hemangiosarcoma / therapy
Humans
Prognosis
Thyroid Neoplasms / diagnosis*
Thyroid Neoplasms / therapy