Representation of Patients With Chronic Kidney Disease in Trials of Cancer Therapy

JAMA. 2018 Jun 19;319(23):2437-2439. doi: 10.1001/jama.2018.7260.


This study characterizes the exclusion of patients with chronic kidney disease (CKD) in randomized clinical trials of drug treatment for bladder, breast, colorectal, lung, and prostate cancer.

MeSH terms

  • Creatinine / blood
  • Humans
  • Neoplasms / complications
  • Neoplasms / drug therapy*
  • Patient Selection*
  • Randomized Controlled Trials as Topic*
  • Renal Insufficiency, Chronic / complications*


  • Creatinine