Commentary: Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice

Front Neurosci. 2018 Jun 6:12:401. doi: 10.3389/fnins.2018.00401. eCollection 2018.

Matthew J Betts^{1

2}, Alexander J Ehrenberg³, Dorothea Hämmerer^{1

4

5}, Emrah Düzel^{1

2

4}

¹ German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
² Institute of Cognitive Neurology and Dementia Research, Otto von Guericke University Magdeburg, Magdeburg, Germany.
³ Memory and Aging Center, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, United States.
⁴ Institute of Cognitive Neuroscience, University College London, London, United Kingdom.
⁵ The Wellcome Trust Centre for Neuroimaging, University College London, London, United Kingdom.

No abstract available

Keywords: hippocampus; learning and memory; locus coeruleus; neuropathology; norepinephrine; tauopathy.

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