Co-occurrence of astrocytoma and astroblastoma: Case report and literature review

Goksel Sali; Robert G Briggs; Andrew K Conner; Ali H Palejwala; Kar-Ming Fung; James D Battiste; Michael E Sughrue

doi:10.1111/neup.12483

Co-occurrence of astrocytoma and astroblastoma: Case report and literature review

Neuropathology. 2018 Oct;38(5):516-520. doi: 10.1111/neup.12483. Epub 2018 Jun 25.

Authors

Goksel Sali¹, Robert G Briggs¹, Andrew K Conner¹, Ali H Palejwala¹, Kar-Ming Fung², James D Battiste³, Michael E Sughrue¹

Affiliations

¹ Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
² Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
³ Department of Neurology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

PMID: 29939429
DOI: 10.1111/neup.12483

Abstract

A 41-year-old man presented to us with left arm and leg weakness and mild word finding difficulties. His preoperative magnetic resonance imaging (MRI) demonstrated abnormal T1 and T2 signal changes in the right temporal lobe and basal ganglia, indicative of possible glioma. An awake craniotomy for right temporal lobectomy was performed and the tumor was resected. Full pathologic workup later revealed the patient had two distinct tumors occurring simultaneously, anaplastic astrocytoma and astroblastoma. We review the literature regarding the treatment of anaplastic astrocytoma and astroblastoma and discuss their co-occurrence.

Keywords: astroblastoma; astrocytoma; brain tumor; case report.

Publication types

Case Reports
Review

MeSH terms

Adult
Astrocytoma / pathology*
Brain Neoplasms / pathology*
Humans
Male
Neoplasms, Multiple Primary / pathology*
Neoplasms, Neuroepithelial / pathology*