Benzathine Penicillin

Excerpt

Benzathine penicillin is formulated from two penicillin G molecules reacting with diphenylethylene diamine. It is active against gram-positive bacteria, including beta-hemolytic streptococci (groups A, B, C, G, H, L, and M) as well as Treponema pallidum and T. carateum. There has been no reported resistance to benzathine penicillin in Streptococcus pyogenes. This activity outlines the indications, mechanism of action, administration, adverse effects, and contraindications when using benzathine penicillin.