The Increasingly Human and Profitable Monoclonal Antibody Market

Trends Biotechnol. 2019 Jan;37(1):9-16. doi: 10.1016/j.tibtech.2018.05.014. Epub 2018 Jun 23.


The monoclonal antibody (mAb) market has changed rapidly in the past 5 years: it has doubled in size, becoming dominated by fully human molecules, launched bispecific molecules, and faced competition from biosimilars. We summarize the market in terms of therapeutic applications, type and structure of mAbs, dominant companies, manufacturing locations, and emerging markets.

Keywords: biosimilars; market analysis; monoclonal antibody.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antibodies, Monoclonal / isolation & purification*
  • Antibodies, Monoclonal / therapeutic use*
  • Global Health
  • Humans
  • Immunologic Factors / isolation & purification*
  • Immunologic Factors / therapeutic use*
  • Immunotherapy / methods*
  • Immunotherapy / trends*


  • Antibodies, Monoclonal
  • Immunologic Factors