A Method for Prediction of Femoral Component of Hip Prosthesis Durability due to Aseptic Loosening by Using Coffin/Manson Fatigue Model

Biomed Res Int. 2018 May 23:2018:9263134. doi: 10.1155/2018/9263134. eCollection 2018.


The purpose of this work is to develop a new model estimate of the fatigue life of a hip prosthesis due to aseptic loosening as a multifactorial phenomenon. The formula developed here is a three-parameter model based on Basquin's law for fatigue, eccentric compression formula for the compressive stress and torsion in the prosthesis due to the horizontal components of the contact force. With our model, we can accurately predict the durability of a hip prosthesis due to the following four parameters: body weight, femoral offset, duration, and intensity of daily physical activities of a patient. The agreement of the prediction with the real life of the prosthesis, observed on 15 patients, is found to be adequate. Based on the formula derived for a particular implant, there was a high degree of concurrence between the model-predicted and actual values of aseptic loosening (durability) proved by the Mann-Whitney U test. By virtue of the validated model, it is possible to predict, quantitatively, the influence of various factors on the hip life. For example, we can conclude that a 10% decrease of a patient's body mass, with all other conditions being the same, causes 5% increase of the hip fatigue life.

MeSH terms

  • Adult
  • Arthroplasty, Replacement, Hip
  • Female
  • Hip Prosthesis*
  • Humans
  • Male
  • Middle Aged
  • Prosthesis Design
  • Prosthesis Failure*
  • Reoperation
  • Retrospective Studies