Acquisition of Multidrug-Resistant Human Immunodeficiency Virus Type 1 Infection in a Patient Taking Preexposure Prophylaxis

Clin Infect Dis. 2018 Aug 31;67(6):962-964. doi: 10.1093/cid/ciy321.

Abstract

We report a case indicating that acquisition of multidrug-resistant human immunodeficiency (HIV) virus type 1 during preexposure prophylaxis with combination tenofovir disoproxil fumarate and emtricitabine or evolution of resistance after HIV seroconversion remains a risk.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Anti-HIV Agents / therapeutic use*
  • Drug Resistance, Multiple, Viral*
  • Emtricitabine / therapeutic use
  • HIV Infections / diagnosis*
  • HIV Infections / prevention & control
  • HIV Seropositivity*
  • HIV-1 / isolation & purification
  • Humans
  • Male
  • Medication Adherence
  • Pre-Exposure Prophylaxis*
  • RNA, Viral / genetics
  • Tenofovir / therapeutic use
  • Thailand

Substances

  • Anti-HIV Agents
  • RNA, Viral
  • Tenofovir
  • Emtricitabine