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Review
. 2018 Jul;14(3):237-245.
doi: 10.1016/j.hfc.2018.02.001.

The Right Heart-Pulmonary Circulation Unit: Physiopathology

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Review

The Right Heart-Pulmonary Circulation Unit: Physiopathology

Robert Naeije et al. Heart Fail Clin. .

Abstract

The most common cause of right heart failure is increased afterload caused by pulmonary hypertension. Right ventricular function adaptation to increased afterload is basically systolic, with secondary increase in dimensions and systemic congestion. Increased right ventricular dimensions and decreased ejection fraction are associated with a decreased survival in severe pulmonary hypertension. Targeted therapies titrated to reverse the right ventricular remodeling dimensions improve survival in severe pulmonary hypertension.

Keywords: Pulmonary hypertension; Reduced ejection fraction; Right heart failure; Right heart pulmonary circulation; Right ventricular function adaptation.

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