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. 1985;92(5):369-77.
doi: 10.1007/BF00327469.

A Cloned Sequence, p82H, of the Alphoid Repeated DNA Family Found at the Centromeres of All Human Chromosomes

A Cloned Sequence, p82H, of the Alphoid Repeated DNA Family Found at the Centromeres of All Human Chromosomes

A R Mitchell et al. Chromosoma. .

Abstract

Clone p82H is a human DNA sequence which hybridises in situ exclusively to the centromeric regions of all human chromosomes. It is composed of approximately 14 tandemly repeated variants of a basic 172 bp sequence, and is related to the alphoid family. The organisation of the family of cross-hybridising sequences, detected by the clone p82H, is described both in the human genome and on certain chromosomes, and its relationship to known sequence families is discussed.

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