A cloned sequence, p82H, of the alphoid repeated DNA family found at the centromeres of all human chromosomes

Chromosoma. 1985;92(5):369-77. doi: 10.1007/BF00327469.

Abstract

Clone p82H is a human DNA sequence which hybridises in situ exclusively to the centromeric regions of all human chromosomes. It is composed of approximately 14 tandemly repeated variants of a basic 172 bp sequence, and is related to the alphoid family. The organisation of the family of cross-hybridising sequences, detected by the clone p82H, is described both in the human genome and on certain chromosomes, and its relationship to known sequence families is discussed.

MeSH terms

  • Base Sequence
  • Centromere / ultrastructure*
  • Chromosomes / ultrastructure*
  • Chromosomes, Human / ultrastructure*
  • Cloning, Molecular*
  • DNA / genetics*
  • DNA Restriction Enzymes
  • DNA Transposable Elements
  • Escherichia coli / genetics
  • Humans
  • Hybrid Cells / cytology
  • Male
  • Nucleic Acid Hybridization
  • Repetitive Sequences, Nucleic Acid
  • Spermatozoa

Substances

  • DNA Transposable Elements
  • DNA
  • DNA Restriction Enzymes

Associated data

  • GENBANK/X02952
  • GENBANK/X02953