Multiple sclerosis and human T-cell lymphotropic retroviruses

Nature. 1985 Nov 14-20;318(6042):154-60. doi: 10.1038/318154a0.


A combination of different types of data suggests that some multiple sclerosis patients respond immunologically to, and have cerebrospinal T cells containing, a retrovirus that is related to, but distinct from, the three types of human T-cell lymphotropic viruses. The role of this virus in multiple sclerosis is uncertain.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Viral / analysis*
  • Antibodies, Viral / cerebrospinal fluid
  • Deltaretrovirus / genetics
  • Deltaretrovirus / immunology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Multiple Sclerosis / microbiology*
  • Nucleic Acid Hybridization
  • RNA, Viral / analysis


  • Antibodies, Viral
  • RNA, Viral