"Chocolate" Gold Nanoparticles-One Pot Synthesis and Biocompatibility

Nanomaterials (Basel). 2018 Jul 5;8(7):496. doi: 10.3390/nano8070496.


The chemical synthesis of nanoparticles can involve and generate toxic materials. Here, we present for the first time, a one pot direct route to synthesize gold nanoparticles (AuNPs) using natural cacao extract as both a reducing and stabilizing agent. The nanoparticles were characterized by UV-visible spectroscopy (UV-VIS), dynamic light scattering (DLS), and transmission electron microscopy (TEM); and have excellent biocompatibility with human primary dermal fibroblasts.

Keywords: cacao; green synthesis; non-cytotoxic.