Diagnosis and Treatment of Vulvar Lichen Sclerosus: An Update for Dermatologists

Am J Clin Dermatol. 2018 Oct;19(5):695-706. doi: 10.1007/s40257-018-0364-7.

Abstract

Vulvar lichen sclerosus is an important skin disease that is common in women in their 50 s and beyond; however, it can also affect females of any age, including children. If not treated, it has the potential to cause significant and permanent scarring and deformity of the vulvar structure. In addition, if untreated, it is associated with a 2-6% lifetime risk of malignant squamous neoplasia of the vulva. Lichen sclerosus has been considered a difficult to manage condition; however, both serious complications can potentially be prevented with early intervention with topical corticosteroid, suggesting that the course of the disease can be treatment modified.

Publication types

  • Review

MeSH terms

  • Administration, Cutaneous
  • Cicatrix / etiology
  • Cicatrix / prevention & control*
  • Dermoscopy
  • Diagnosis, Differential
  • Female
  • Glucocorticoids / therapeutic use*
  • Humans
  • Lichenoid Eruptions / diagnosis
  • Long-Term Care / methods
  • Psoriasis / diagnosis
  • Remission Induction / methods
  • Severity of Illness Index
  • Skin / diagnostic imaging
  • Skin / pathology
  • Time Factors
  • Treatment Outcome
  • Vulva / diagnostic imaging
  • Vulva / pathology
  • Vulvar Lichen Sclerosus / complications
  • Vulvar Lichen Sclerosus / diagnosis
  • Vulvar Lichen Sclerosus / drug therapy*
  • Vulvar Lichen Sclerosus / pathology
  • Vulvar Neoplasms / etiology
  • Vulvar Neoplasms / prevention & control*

Substances

  • Glucocorticoids