The past decade has witnessed the use of highlevel features in saliency prediction for both videos and images. Unfortunately, the existing saliency prediction methods only handle high-level static features, such as face. In fact, high-level dynamic features (also called actions), such as speaking or head turning, are also extremely attractive to visual attention in videos. Thus, in this paper, we propose a data-driven method for learning to predict the saliency of multiple-face videos, by leveraging both static and dynamic features at high-level. Specifically, we introduce an eye-tracking database, collecting the fixations of 39 subjects viewing 65 multiple-face videos. Through analysis on our database, we find a set of high-level features that cause a face to receive extensive visual attention. These high-level features include the static features of face size, center-bias and head pose, as well as the dynamic features of speaking and head turning. Then, we present the techniques for extracting these high-level features. Afterwards, a novel model, namely multiple hidden Markov model (M-HMM), is developed in our method to enable the transition of saliency among faces. In our MHMM, the saliency transition takes into account both the state of saliency at previous frames and the observed high-level features at the current frame. The experimental results show that the proposed method is superior to other state-of-the-art methods in predicting visual attention on multiple-face videos. Finally, we shed light on a promising implementation of our saliency prediction method in locating the region-of-interest (ROI), for video conference compression with high efficiency video coding (HEVC).