Location estimation within the human body by means of wireless signals is becoming popular for a variety of purposes, including wireless endoscopy using camera pills. The precision of wireless ranging in any medium is contingent upon the methodology employed. Two of the most popular wireless tracking methods are received signal strength (RSS) and time of arrival (TOA). The scope of this study is an assessment of the precision of TOA- and RSS-based ranging in the proximity of anthropomorphic tissue by means of simulation software designed to mimic signal transmission in the human body environment. Software simulations of wireless signals traveling within a human body are exceptionally challenging and require extensive computational resources. We created a rudimentary, MATLAB script using the finite-difference time-domain (FDTD) method to simulate the signal transmission inside and outside a human body and correlated the simulation outcomes of this script with the high-end commercial finite-element method (FEM) tool, ANSYS HFSS. First, we demonstrated that the FDTD modeling produces similar outcomes. Next, we employed the script to emulate the RSS and TOA of the wide bandwidth radio transmission within the human body for wireless ranging and estimated the accuracy of each technology. The precision of both methods was also evaluated with the Cramer-Rao lower bound (CRLB), which is frequently used to estimate the ranging methodologies and the effect of human tissue and its motion.