Lysosomal hydrolases of the epidermis. I. Glycosidases

Br J Dermatol. 1975 Jul;93(1):1-10. doi: 10.1111/j.1365-2133.1975.tb06468.x.


Seven distinct glycosidases (EC 3.2) have been characterized in guinea-pig epidermis. Their properties indicate them to be of lysosomal origin. The 'profile' of the epidermal glycosidases is significantly different from that reported for whole skin, the activities of beta-galactosidase and beta-acetylglucosaminidase being very high and those of the remaining enzymes relatively low in epidermis.

MeSH terms

  • Acetylglucosaminidase / metabolism
  • Animals
  • Galactosidases / metabolism
  • Glycoside Hydrolases / metabolism*
  • Guinea Pigs
  • Hydrogen-Ion Concentration
  • Kinetics
  • Lysosomes / enzymology*
  • Skin / enzymology*


  • Galactosidases
  • Glycoside Hydrolases
  • Acetylglucosaminidase