In: Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006.


No information is available on the clinical use of semaglutide during breastfeeding. Because semaglutide is a peptide molecule with a molecular weight of 4113 Da and is over 99% protein bound, the amount in milk is likely to be very low. Furthermore, semaglutide is only 0.4% to 1% orally absorbed, so it is unlikely to adversely affect the breastfed infant.

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