Limited evidence indicates that use of clomipramine during breastfeeding is acceptable. For women who were taking clomipramine during pregnancy, the amount of drug in breastmilk may be insufficient to prevent neonatal withdrawal symptoms in breastfed infants. A safety scoring system finds clomipramine to be possibly used with caution during breastfeeding.[1] For use as an antidepressant, clomipramine may be less desirable than other antidepressants that have been studied more thoroughly.