Rhinovirus Species in Children With Severe Bronchiolitis: Multicenter Cohort Studies in the United States and Finland

Pediatr Infect Dis J. 2019 Mar;38(3):e59-e62. doi: 10.1097/INF.0000000000002141.


In this analysis of 2 prospective multicenter, multi-year cohorts of children hospitalized for bronchiolitis in the United States and Finland, 306 rhinovirus infections were genotyped. Rhinovirus-A and -C species were predominant in the US study, while rhinovirus-C species was predominant in the Finland study. In both cohorts, there were no significant between-species differences in clinical characteristics, including acute severity measures.

Publication types

  • Multicenter Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Bronchiolitis, Viral / epidemiology*
  • Female
  • Finland / epidemiology
  • Hospitalization / statistics & numerical data*
  • Humans
  • Infant
  • Male
  • Molecular Typing
  • Picornaviridae Infections / epidemiology*
  • Prospective Studies
  • Rhinovirus / classification
  • Rhinovirus / isolation & purification*
  • Severity of Illness Index
  • United States / epidemiology