Reviewing the therapeutic role of budesonide in Crohn's disease

Gastroenterol Hepatol. 2018 Aug-Sep;41(7):458-471. doi: 10.1016/j.gastrohep.2018.05.013. Epub 2018 Jul 12.
[Article in English, Spanish]


Oral budesonide is a glucocorticoid of primarily local action. In the field of digestive diseases, it is used mainly in inflammatory bowel disease, but also in other indications. This review addresses the pharmacology, pharmacodynamics and therapeutic use of budesonide. Its approved indications are reviewed, as well as other clinical scenarios in which it could play a role, in order to facilitate its use and improve the accuracy of its prescription.

Keywords: Budesonida; Budesonide; Colitis ulcerosa; Crohn's disease; Enfermedad de Crohn; Enfermedad inflamatoria intestinal; Inflammatory bowel disease; Ulcerative colitis.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / adverse effects
  • Anti-Inflammatory Agents / pharmacology
  • Anti-Inflammatory Agents / therapeutic use*
  • Budesonide / administration & dosage
  • Budesonide / adverse effects
  • Budesonide / pharmacology
  • Budesonide / therapeutic use*
  • Colitis, Ulcerative / drug therapy
  • Controlled Clinical Trials as Topic
  • Crohn Disease / drug therapy*
  • Crohn Disease / surgery
  • Humans
  • Ileostomy
  • Postoperative Complications / prevention & control
  • Practice Guidelines as Topic


  • Anti-Inflammatory Agents
  • Budesonide