Ocrelizumab for multiple sclerosis

Drug Ther Bull. 2018 Jul;56(7):80-84. doi: 10.1136/dtb.2018.7.0646.

Abstract

▼Ocrelizumab (Ocrevus - Roche Registration GmbH) has received marketing authorisation approval from the European Medicines Agency (EMA) for the treatment of adults with multiple sclerosis.1,2 It is the first drug to be licensed for use in early primary progressive multiple sclerosis and relapsing forms of multiple sclerosis. Here, we review the evidence for the safety and effectiveness of ocrelizumab.

MeSH terms

  • Adult
  • Antibodies, Monoclonal, Humanized / adverse effects
  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • Guidelines as Topic
  • Humans
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use
  • Multiple Sclerosis / drug therapy*

Substances

  • Antibodies, Monoclonal, Humanized
  • Immunosuppressive Agents
  • ocrelizumab